Diagnosis and treatment of various pediatric and adolescent gynecological diseases, especially in the diagnosis and treatment of childhood precocious puberty, Turner syndrome (TS), vulvar pruritus, vulvar sclerosis lichenification, adolescent polycystic ovary syndrome (PCOS), abnormal uterine bleeding (AUB), vulvovaginitis of young girls, vaginal foreign bodies and disorder of sexual development (DSD), etc.

Study on the etiology and pathogenesis of vulvar sclerosis lichenification, vulvovaginitis in children, treatment of polycystic ovary syndrome in adolescence, HPV infection in adolescents and vaginal microecology, Mayer-Rokitansky- Küster-Hauser (MRKH) syndrome.